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Radiation Science & Technology Major

Prof. Il Lae Jung 정일래

 

Email : ex-jil7147@kaeri.re.kr / ex-jil7147@ust.ac.kr Tel : +82-42-868-8036





2004 ~ present Principal Researcher, KAERI

2010 ~ present Professor, Radiation Science & Technology, UST

2022 ~ present CTO, Insgen Co. Ltd.




Anti-Cancer Drug development & Radiation therapy

Functional Food Development

Basic Research for Genetic Scissor and Adaptive Evolution




1992 B.S. Biological Science, Sungkyunkwan Univ

2003 M.S. Biological Science, Sungkyunkwan Univ

2010 Ph.D. Biological Science, Sungkyunkwan Univ




2007 ~ 2008 Visiting Scholor, SCRIPPS Research Institute, USA

2001 ~ 2004 Post Doc/Senior Research Scientist, Korea Atomic Energy Research Institute




(On-going)

  • Mid-career Research Project (NRF) ‘21~24 (Fund : 500 million won)

  • Ecological Mimicry Research Project (KEIT) ‘19~23 (Fund : 1.8 billion won)

  • Exosome Research Project (Daejeon City) ‘23~24 (Fund : 150 million won)




(International Journal, SCI)

  • Silver Nanoclusters Serve as Fluorescent Rivets Linking Hoogsteen Triplex DNA and Hairpin-Loop DNA Structures. Jung IL* (First Author) Aug. 2022 ACS Nano (IF 18.03)

  • Transcriptome analysis revealed that jasmonic acid biosynthesis/signaling is involved in plant response to Strontium stress. Jung IL* (Corresponding Author) Apr. 2022. Ecotoxicology and Environemntal Safety. (IF 7.13)

  • Strontium stress disrupts miRNA biogenesis by reducing HYL1 protein levels in Arabidopsis. Jung IL* (Corresponding Author) Aug. 2022. Ecotoxicology and Environemntal Safety. (IF 7.13)

  • Noncanonical Head-to-Head Hairpin DNA Dimerization Is Essential for the Synthesis of Orange Emissive Silver Nanoclusters. Jung IL* (First Author) Jun. 2020 ACS Nano (IF 18.03)

  • The Structural Shift of a DNA Template Between a Hairpin and a Dimer Tunes the Emission Color of DNA-templated AgNCs. Nanoscale. Nov. 2018. Pratik S, Choi SW, Nagda R, Ceczy R, Cho SK, Bhang YJ, Kin TW, Song TY, Lee PH, Kang JH, Waaben P, Thulstrup PW, Bjerrum MJ, Jung IL*, and Yang SW (Co-corresponding author) (IF=6.970)

  • A potential oral anticancer drug candidate, Moringa oleifera leaf extract, induces the apoptosis of human hepatocellular carcinoma cells. Oncol. Lett. 2015. Jung IL

  • Cesium toxicity alters microRNA processing and AGO1 expressions in Arabidopsis thaliana. PLos One 2015. Jung IL, Ryu MY, Cho SK, Shah P, Lee JH, Bae HS, Kim IG, Yang SW

  • Soluble extract from Moringa oleifera leaves with a new anticancer activity. . PLoS One 2014. Jung IL.

  • Knockdown of the Dickkopf3 gene induces apoptosis in a lung adenocarcinoma. Int. J. Mol. Med. 2010. Jung IL, Kang HJ, Kim KC, Kim IG

  • PTEN/pAkt/p54 signalling pathway correletes with the radioresponse of non-small cell lung cancer. Int. J. Mol. Med. 2010. Jung IL, Kang HJ, Kim KC, Kim IG

  • Polyamines as a signalling molecule for controlling an adaptive mutation. Biochemstry (Moscow). 2008. Jung IL, Kim IG

  • The RpoS-mediated regulation of isocitrate dehydrogenase gene expression in Escherichia coli.

  • Curr. Microbiol. 2006. Jung IL, Kim SK, Kim IG

  • Spontaneous liberation of intracellular polyhydroxybutyrate granules in Escherichia coli. Res. Microbiol. 2005. Jung IL, Phyo KH, Kim KC, Park HK, Kim IG

  • RpoS-Mediated Growth-Dependent Expression of the Escherichia coli tkt Genes Encoding Transketolases Isoenzymes. Curr.Microbiol. Jun. 2005. Jung IL, Phyo KH, Kim IG

  • GAD 67KD antisense in colon cancer cells inhibits cell growth and sensitizes to butyrate and pH reduction and H2O2 and gamma-radiation. Arch. Biochem. Biophys. Oct. 2004. Moon MS, Cho EW, Byun HS, Jung IL, Kim IG

  • Thiamine protects against paraquat-induced damage: scavenging activity of reactive oxygen species. Environ.Toxicol. Pharm. Dec. 2003. Jung IL, Kim IG

  • Abnormal growth of polyamine-deficient Escherichia coli mutant is partially caused by oxidative stress-induced damage. Arch. Biochem. Biophys. Oct. 2003. Jung IL, Oh TJ, Kim IG

  • Polyamines and glutamate decarboxylase-based acid resistance in Escherichia coli. J. Biol. Chem. Jun. 2003. Jung IL, Kim IG

  • Transcription of ahpC, katG, and katE genes in Escherichia coli is regulated by polyamines: polyamine-deficient mutant sensitive to H2O2-induced oxidative damage. Biochem. Biophys. Res.Commun. Feb. 2003. Jung IL, Kim IG

  • Polyamines reduce paraquat-induced soxS and its regulon expression in Escherichia coli. Cell Biol. Toxicol. Feb. 2003. Jung IL, Kim IG

  • The Escherichia coli SOS gene sbmC is regulated by H-NS and RpoS during the SOS induction and stationary growth phase. Biochem. Biophys. Res. Commun. Nov. 2001. Oh TJ, Jung IL, Kim IG


(Patent)

  • Moringa oleifera extract as an anticancer drug candidate. Jung IL, Kang SC Nov. 2017/ May. 2018. Korea and China. Pat No. 10-1803852/ Pat No. ZL201410253975

  • Composition for preventing hair loss and promoting hair growth. Jung IL, Kang SC Sep. 2017. Korea. Pat No. 10-1776587.

  • Anti-diabetic effect of Banaba and Peony complex extract. Jung IL, Kang SC May. 2017. Korea. Pat No. 10-1734325

  • Cs decontamination by Korea Glasswort. Jung IL, Park DH, Kim MJ, Son AR, Kim IG Nov. 2015. Korea. Korea. Pat No. 15-1574741

  • Overproduction of polyhydroxybutyrate in E. coli. Jung IL, Kim IG. Aug. 2010. USA Pat. No. 7,771,964

  • Overproduction of polyhydroxybutyrate in E. coli. Jung IL, Kim IG. Oct. 2009. Japan. Pat No. 4384943

  • Overproduction of polyhydroxybutyrate in E. coli. Jung IL, Kim IG. Dec. 2006. Korea. Pat No. 656529

  • The method for the overproduction of polyhydroxybutyrate using two-step cultivation technique. Jung IL, Kim IG. Jun. 2003. South Korea

  • The method for the increase of cell sucseptiblity by regulating rpoS gene expression in Escherichia coli. Jung IL, Kim IG. Jul. 2007. Korea. Pat No 745357




  • 2018 – Present Science Consultant, Korea Foundation for the Advancement of Science and Creativity

  • 2018 – Present Member of Trustee, Korea Society of Radiation Bioscience

  • 2005 – Present Member of Trustee, Korean Society of Toxicogenomics and Toxicoproteomics, Korea

  • 2001 – Present Science Ambassador (lecturer for popularization of science), Korea Science Foundation (KSF), Korea




  • Radiation Biology & Molecular Biology (UST 2020-present)

  • Radiation Biology (Jeonbook Univ 2012-2013)

  • Radiation Biology (Cheongjoo Univ 2009-2010)

  • Science history (Sungkyunkwan Univ 1998-2001)


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